This means that Sonata medication has the potential to be abused and can create a dependency, leading to Sonata addiction. Sonata Sleeping Pill is a Schedule IV Prescription Medication. This is in contrast to other sedative-hypnotics such as benzodiazepines, which have the same mechanisms of action but non-selectively bind all GABA receptors, possessing neuromuscular relaxative and anticonvulsant properties in addition to sedation and hypnosis. Selectivity results from the discriminant binding of Z-drugs to a particular subset of GABA receptors within our central nervous systems, which only allows Z-drugs to produce hypnosis. The “selective hypnotic” effects of this drug are important. It mediates its selective hypnotic effects, by binding with the GABA receptors in the Central Nervous System (CNS) and potentiating/promoting the decreased neuronal excitability produced by the action of the inhibitory neurotransmitter, gamma-Aminobutyric acid (GABA). Although not related in structure, it does share the same mechanisms of action as other sedative-hypnotics. Zaleplon is a hypnotic or sleep agent that is not related in structure to other sedative-hypnotics such as benzodiazepines and barbiturates. Generic Sonata or Zaleplon, as mentioned above, belongs to a novel group of drugs known as “Z-drugs” that appeared on the pharmaceutical market during the 1980s. Therefore, due to the pertinence of this topic, this article will endeavor to briefly describe and review information regarding Zaleplon’s mechanism of action, correct dosing and administration, various Zaleplon side effects, and contraindications, as well as abuse, addiction, and its successful treatment. This is particularly concerning, as The United States Centers for Disease Control and Prevention reports an increase in the number of prescriptions for sleep aids in the past two decades. However, clinical experience has shown that the development of tolerance, followed by Sonata abuse and Sonata addiction can be expected, especially with high doses and prolonged use. The Sonata sleeping pill, along with its congeners Imovane (Zopiclone) and Ambien (Zolpidem), were originally developed and promoted as having less potential for dependence and abuse, as well as fewer second-day side effects. Zaleplon(Sonata) is one such agent, belonging to a group of sleeping pills, new, novel, non-benzodiazepine sedative-hypnotics known as “Z compounds” or “Z-drugs”. As a result, great efforts have been made to develop new novel agents for the treatment of insomnia. The sequelae of insomnia can have grave consequences on the physical, social, and emotional health and wellbeing of individuals.
Insomnia, which refers to the presence of long sleep latency, frequent nocturnal awakenings, prolonged periods of wakefulness, or frequent nocturnal arousals is a commonly reported problem worldwide, with prevalence rates ranging from 33-45%.
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