Cellular adhesion is a complex process in which transmembrane receptors such as integrins are recruited, activated and consequently bind to the extracellular matrix. The tension generated in the actin cytoskeleton determines cellular adhesion, spread area, motility, proliferation, differentiation and apoptosis. This does not alter the authors' adherence to PLOS ONE Editorial policies and criteria. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: Rafael Aldabe is a PLOS ONE Editorial Board member. This work was supported by the UTE project CIMA (to R.A.), the Spanish Ministry of Science and Innovation, ISCIII (project PS09/00393) (to R.A.) and the European Research Council (ERC) through project ERC-2012-StG 306751 and the Spanish Ministry of Economy and Competitiveness (DPI2012-38090-C03-01) (J.M.G.). is recipient of ISCIII a Consolidation Program grant. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.įunding: R.A. Received: JanuAccepted: AugPublished: September 30, 2014Ĭopyright: © 2014 Elosegui-Artola et al. PLoS ONE 9(9):Įditor: Florence Janody, Instituto Gulbenkian de Ciência, Portugal (2014) Image Analysis for the Quantitative Comparison of Stress Fibers and Focal Adhesions. Citation: Elosegui-Artola A, Jorge-Peñas A, Moreno-Arotzena O, Oregi A, Lasa M, García-Aznar JM, et al.
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